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REFLECTIONS
                                                                                                                   Dyslipidaemia
     Dyslipidaemia Global Newsletter #11 2026


     aggressive reductions in cholesterol did not come at the cost of patient safety; no significant between-group differences in the
     incidence of serious safety events or adverse events leading to the discontinuation of the drug were found.   Dyslipidaemia

                         Key subgroup analyses for the primary efficacy endpoints (3-point MACE)














































     CI, confidence interval; LDL, low-density lipoprotein; MACE, major adverse cardiovascular event.


     In conclusion, adding a PCSK9i to baseline lipid-lowering
     therapy provides significant, long-term CV benefits for patients
     earlier on the atherosclerotic risk continuum. Aggressively
     lowering LDL-C with evolocumab can safely and effectively
     prevent first major CV events in high-risk patients with
     atherosclerosis or diabetes before an MI or stroke ever occurs.

                                                                         CLICK HERE
                                                                         LISTEN TO DR. NANETTE KASS
                                                                         WENGER DISCUSS WITH AUTHOR
                                                                         DR. ERIN A. BOHULA THE VESALIUS-CV
                                                                         TRIAL: EFFECT OF EVOLOCUMAB IN
              CLICK HERE                                                 PATIENTS AT CV RISK WITHOUT PRIOR
              FOR THE LINK TO FULL ARTICLE                               MI OR STROKE (9 MIN)






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